CJC-1295 vs Ipamorelin
This page has not yet been reviewed by a credentialed medical professional. It is educational and is not medical advice.
Short answer: They work on the growth hormone axis in different ways: CJC-1295 mimics GHRH and lasts days, ipamorelin mimics ghrelin and lasts hours. Both have small human studies of hormone levels, and neither has outcome data.
| CJC-1295 Human trials | Ipamorelin Human trials | |
|---|---|---|
| Target | GHRH receptor | Ghrelin (GHS) receptor |
| Evidence grade | Human trials (hormone markers only) | Human trials (pharmacology; one missed phase 2) |
| Duration of action | Half-life roughly 6 to 8 days | Half-life roughly 2 hours |
| Best human evidence | Two placebo-controlled trials in healthy adults | Dose-escalation study and phase 2 ileus trial |
| Outcome data (muscle, fat, aging) | None | None |
| US status | Not approved | Not approved |
| WADA | Prohibited | Prohibited |
Takeaway
They are often sold together, but no controlled trial has tested the combination.
FAQ
Should CJC-1295 and ipamorelin be taken together?
There is no controlled human evidence on the combination for any outcome.